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Laboratory for Stem Cells and Regenerative Biomedical Engineering

Dr. Kisuk Yang works in the fields of medical devices, stem cell and tissue engineering. His laboratory focuses on the design and testing of bioengineered tissues, which are composed of mainly stem cell-derived cells (e.g., neural cells, pancreatic cells, and osteogenic cells) and tissue-specific extracellular matrix scaffolds. The overall goal is to develop new strategies to assemble and test bioengineered constructs capable of restoring tissue function. 

 

The major goals of the laboratory are i) to harness the power of stem cell niches (e.g., 3D microenvironment, ECM, cell-cell interaction, and cell signaling) to guide stem cell differentiation and/or tissue remodeling in vitro and in vivo, and ii) to understand and harness the interaction between inflammatory cells and bioengineered tissue constructs in order to improve survival and function.

Our Research

백신 생산 라인

Development of Functional Biomaterials

We fabricated co-culture system that can be used to construct interconnected tissue. This system is also available to study biological mechanisms.

샘플

Engineering of Stem Cell Microenvironment Mimicking Device

Mimicking the microphysiological environment and recapitulating cell-cell interactions to model tissue. 

m-PO dapi_cCasps3 2.tif

Fabrication of Multi-organ Culture Tool

Multi-organ device for analysis of interactions between organs, disease modeling, and drug testing

현미경 세포 분석

Stem Cell Therapy Using Encapsulation Technology

Macroencapsulation devices (MEDs) for protect insulin-producing cells while allowing nutrient and insulin exchange, aiming for long-term survival.

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